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논문 기본 정보

자료유형
학술저널
저자정보
Yong Min Cho (Smartive Corporation)
저널정보
환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Health and Toxicology Vol.32
발행연도
2017.12
수록면
69 - 76 (8page)

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In this study, the associations between mercury (Hg) exposure and cholesterol profiles were analyzed, and increased Hg levels and cholesterol profiles according to the amount of fish consumption were evaluated. Data on levels of blood Hg, the frequency of fish consumption, total blood cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) in 3951 adults were obtained from the Korea National Health and Nutrition Examination Survey 2010-2011 database. To compare the distribution for each log-transformed indicator, Student’s t -test and analysis of variance were carried out, and the groups were classified according to the frequency of fish consumption through linear regression analysis; the association between Hg level and cholesterol profiles in each group was analyzed. The blood Hg levels (arithmetic mean, median, and geometric mean) for all target participants were 4.59, 3.66, and 3.74 μg/L, respectively. The high cholesterol group, low HDL-C group, and high TG group showed a statistically and significantly higher blood Hg level than the low-risk group. In both sexes, as the frequency of fish consumption increased, blood Hg level also increased, but TC, HDL-C, LDL-C, and TG did not show a similar trend. Increased blood Hg level showed a significant association with increased TC and LDL-C. This statistical significance was maintained in the group with less frequent fish consumption (〈4 times per month), but the group with frequent fish consumption (〉8 times per month) did not show a similar trend. The results of this study suggest that fish consumption increases the level of Hg exposure, and that as the level of Hg exposure increases, the levels of cholesterol profiles increase. However, this study also suggests that the levels of cholesterol profiles in those with frequent fish consumption can be diminished.
#Mercury #Methylmercury #Fish consumption #Cholesterol profiles #Korea National Health and Nutrition Examination Survey

목차

INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES

참고문헌 (39)

참고문헌 신청
Curtis D Klaassen CD, Casarett LJ, Doull J. Casarett and Doull’s toxicology: the basic science of poisons. 8th ed. New York: Mc- Graw-Hill Education; 2013, p. 947-950. google schola Xu Y, Khoury JC, Sucharew H, Dietrich K, Yolton K. Low-level gestational exposure to mercury and maternal fish consumption: associations with neurobehavior in early infancy. Neurotoxicol Teratol 2016;54:61-67. Yin L, Yu K, Lin S, Song X, Yu X. Associations of blood mercury, inorganic mercury, methyl mercury and bisphenol A with dental surface restorations in the U.S. population, NHANES 2003-2004 and 2010-2012. Ecotoxicol Environ Saf 2016;134:213-225. Ilmiawati C, Yoshida T, Itoh T, Nakagi Y, Saijo Y, Sugioka Y, et al. Biomonitoring of mercury, cadmium, and lead exposure in Japanese children: a cross-sectional study. Environ Health Prev Med 2015;20(1):18-27. Kim NS, Lee BK. National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population. Int Arch Occup Environ Health 2011;84(1):53-63.

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