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논문 기본 정보

자료유형
학술저널
저자정보
Ji-Hyun Nam (Korea Centers for Disease Control and Prevention) Ji-Hye Shin (Chungbuk National University) Tae-Hun Kim (Korea Atomic Energy Research Institute) Seungho Yu (Korea Atomic Energy Research Institute) Dong-Hun Lee (Chungbuk National University)
저널정보
대한환경공학회 Environmental Engineering Research Environmental Engineering Research 제25권 제4호
발행연도
2020.8
수록면
614 - 621 (10page)

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초록· 키워드

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Antibiotic pollution is one of the factors contributing to the spread of antibiotic-resistant bacteria in the environment. Advanced oxidation and irradiation processes have been introduced to eliminate antibiotics from water and wastewater. However, few studies have reported the toxic effects of residual antibiotics and their byproducts induced by a treatment system. In this study, we compared the efficacies of chemical (high-performance liquid chromatography (HPLC)) and biological (antimicrobial susceptibility test) assays for measuring the concentrations of residual antibiotics after gamma irradiation for degrading amoxicillin, cephradine, lincomycin, and tetracycline. The concentrations of residual antibiotics estimated using the two assay methods were almost identical, except cephradine. In the case of cephradine, inhibited bacterial growth was observed that was equivalent to twice the concentration measured by HPLC in the samples subjected to gamma irradiation. The observed inhibition of bacterial growth suggested the generation of potentially toxic intermediates following antibiotic degradation. These results indicate that biological and chemical assays should be used in concert for monitoring antibiotic contamination and the toxic derivatives of antibiotic degradation. The results demonstrate that these four antibiotics can be decomposed by 2.0 kGy gamma-irradiation without toxic effects of their byproducts.

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ABSTRACT
1. Introduction
2. Experimental
3. Results and Discussion
4. Conclusions
References

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UCI(KEPA) : I410-ECN-0101-2020-539-000378692