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논문 기본 정보

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학술저널
저자정보
Lee, Hyunjong (Department of Nuclear Medicine, Seoul National University Hospital) Paeng, Jin Chul (Department of Nuclear Medicine, Seoul National University Hospital) Kim, Kyung Hwan (Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital) Cheon, Gi Jeong (Department of Nuclear Medicine, Seoul National University Hospital) Lee, Dong Soo (Department of Nuclear Medicine, Seoul National University Hospital) Chung, June-Key (Department of Nuclear Medicine, Seoul National University Hospital) Kang, Keon Wook (Department of Nuclear Medicine, Seoul National University Hospital)
저널정보
대한핵의학회 Nuclear medicine and molecular imaging : NMMI Nuclear medicine and molecular imaging : NMMI 제52권 제1호
발행연도
2018.1
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46 - 52 (7page)

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Purpose Herein, we report characteristics of $^{18}F$-fluorodeoxyglucose (FDG) uptake in abdominal aortic aneurysms (AAAs) during a long-term follow-up. In addition, we investigated the association between FDG uptake and the physician decision to perform an intervention. Methods We performed a retrospective review of 42 patients with AAAs who underwent FDG positron emission tomography (PET)/computed tomography (CT). The size of the AAA was measured in serial CT or PET/CT images. The long-term growth rate of AAAs was calculated by linear regression of the size change. Maximal SUV of the AAA ($SUV_{AAA}$) and mean SUV of the blood pool ($SUV_{Blood}$) were measured in PET/CT fusion images. To assess the FDG uptake of AAAs, the target-to-background ratio (TBR) was defined as the ratio of $SUV_{AAA}$ to $SUV_{Blood}$. We compared FDG uptake of AAAs with the long-term growth rate of AAAs and clinical data. Results TBR was not significantly different between patients with and without significant growth ($1.55{\pm}0.20$ vs. $1.57{\pm}0.14$; P = 0.5599). However, in patients with significant growth, TBR exhibited a significant positive correlation with the growth rate ($r^2=0.2601$, P = 0.0306). TBR also exhibited a significant difference between patients with and without intervention (P = 0.0228). Conclusion FDG uptake of AAA is associated with long-term growth of AAAs in a specified group that exhibits growth. FDG PET/CT may only be effective in predicting the long-term growth of AAAs in specific subgroups of patients. It is also suggested that FDG PET is potentially related to the clinical conditions of AAA patients who need surgical or interventional treatment.
#FDG #PET/CT #Abdominal aortic aneurysm #Intervention

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참고문헌 (29)

참고문헌 신청
Saucy F / 2015 / Abdominal aortic aneurysm: what about screening? / Curr Pharm Des 21:4084~4087 Crossref Schermerhorn ML / 2015 / Long-term outcomes of abdominal aortic aneurysm in theMedicare population / N Engl J Med 373:328~338 Crossref Ballard DJ / 2008 / Surgery for small asymptomatic abdominal aortic aneurysms / Cochrane Database Syst Rev google schola Tanios F / 2015 / Interaction of biomechanics with extracellular matrix components in abdominal aortic aneurysm wall / Eur J Vasc Endovasc Surg 50:167~174 Crossref Larsson E / 2011 / Analysis of aortic wall stress and rupture risk in patients with abdominal aortic aneurysm with a gender perspective / J Vasc Surg 54:295~299 Crossref

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