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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 26 - 29 (4page)
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Purpose: Sentinel lymph node biopsy (SLNB) is a well-established staging procedure for patients with early breast cancer who have clinically negative axillary lymph node. However, no consensus exists about the number of sentinel lymph nodes (SLN) that should be removed based on radioactivity counts in breast cancer. We reviewed and analyzed cases in which more than one SLN was detected and there was at least one pathologically positive node. Methods: We retrospectively studied breast cancer patients who underwent lymphoscintigraphy with injection of a radioactive colloid and SLNB along with intraoperative determination of radioactive counts of lymph nodes using a gamma probe between 2006 and 2018. In total 326 patients with more than one radioactive SLN were enrolled in this study. Results: Fifty-four patients had nodal metastases, of whom 46 (85.2%) had metastases in the hottest lymph node. All metastatic SLNs were identified as one of the first three lymph nodes dissected. The lowest radioactive count of a positive SLN corresponded to 10% of that of the hottest node. Conclusion: We suggest that removal of the first three lymph nodes or nodes covered by the “10% rule” is sufficient in SLNB for patients with breast cancer.
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참고문헌 (15)
참고문헌 신청
Collins CD / 2005 / The sentinel node in breast cancer : an update / Cancer Imaging 5:S3~9
Eun Jeong Ban / 2011 / How Many Sentinel Lymph Nodes Are Enough for Accurate Axillary Staging in T1-2 Breast Cancer? / Journal of Breast Cancer 14(4):296~300
Colakoglu MK / 2018 / Bio-logical subtypes of breast cancer and sentinel lymph node biopsy / Eur J Breast Health 14:100~104
Yi M / 2008 / How many sentinel lymph nodes are enough during sentinel lymph node dissection for breast cancer? / Cancer 113:30~37
Giuliano AE / 2017 / Effect of axillary dissection vs no axillary dissec-tion on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis : the ACOSOG Z0011(alliance)randomized clinical trial / JAMA 318:918~926
Eun Jeong Ban / 2011 / How Many Sentinel Lymph Nodes Are Enough for Accurate Axillary Staging in T1-2 Breast Cancer? / Journal of Breast Cancer 14(4):296~300
Colakoglu MK / 2018 / Bio-logical subtypes of breast cancer and sentinel lymph node biopsy / Eur J Breast Health 14:100~104
Yi M / 2008 / How many sentinel lymph nodes are enough during sentinel lymph node dissection for breast cancer? / Cancer 113:30~37
Giuliano AE / 2017 / Effect of axillary dissection vs no axillary dissec-tion on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis : the ACOSOG Z0011(alliance)randomized clinical trial / JAMA 318:918~926
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