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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국의학물리학회 의학물리 의학물리 제24권 제3호
- 발행연도
- 2013.9
- 수록면
- 145 - 153 (9page)
- DOI
- http://dx.doi.org/10.14316/pmp.2013.24.3.145
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초록· 키워드
오류제보하기
Stereotactic body radiation therapy (SBRT) is increasingly used to treat spinal metastases. To achieve the higheststeep dose gradients and conformal dose distributions of target tumors, intensity-modulated radiation therapy(IMRT) and volumetric-modulated arc therapy (VMAT) techniques are essential to spine radiosurgery. The purposeof the study was to qualitatively compare IMRT and VMAT techniques with International Spine RadiosurgeryConsortium (ISRC) contoured consensus guidelines for target volume definition. Planning target volume (PTV)was categorized as TB, TBPT and TST depending on sectors involved; TB (vertebral body only), TBPT (vertebral body+pedicle+transverse process), and TST (spinous process+transverse process). Three patients treated for spinaltumor in the cervical, thoracic, and lumbar region were selected. Eacg tumor was contoured by the definitionfrom the ISRC guideline. Maximum spinal cord dose were 12.46 Gy, 12.17 Gy and 11.36 Gy for TB, TBPT andTST sites, and 11.81 Gy, 12.19 Gy and 11.99 Gy for the IMRT, RA1 and RA2 techniques, respectively. Averagefall-off dose distance from 90% to 50% isodose line for TB, TBPT, and TST sites were 3.5 mm, 3.3 mm and3.9 mm and 3.7 mm, 3.7 mm and 3.3 mm for the IMRT, RA1 and RA2 techniques, respectively. For the mostcomplicated target TBPT sites in the cervical, thoracic and lumbar regions, the conformity index of the IMRT, RA1and RA2 is 0.621, 0.761 and 0.817 and 0.755, 0.796 and 0.824 for rDHI. Both IMRT and VMAT techniquesdelivered high conformal dose distributions in spine stereotactic radiosurgery. However, if the target volumeincludes the vertebral body, pedicle, and transverse process, IMRT planning resulted in insufficient conformityindex, compared to VMAT planning. Nevertheless, IMRT technique was more effective in reducing the maximumspinal cord dose compared to RA1 and RA2 techniques at most sites.
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참고문헌 (31)
참고문헌 신청
Benedict SH / 2010 / AAPM Radiation Therapy Committee Task Group 101: stereotactic body radiation therapy / Med Phys 37:4078~4101
Matuszak MM / 2010 / Clinical applications of volumetric modulated arc therapy / Int J Radiat Oncol Biol Phys 77:608~616
Sahgal A / 2008 / Stereotactic body radiosurgery for spinal metastases: a critical review / Int Radiat Oncol Biol Phys 71:652~665
Ingrid TK / 2010 / Volumetric modulated arc therapy versus conventional intensity modulated radiation therapy for stereotactic spine radiotherapy: A planning study and early clinical data / Radiother Oncol 94:224~228
Nelson JW / 2009 / Stereotactic body radiotherapy for lesions of the spine and paraspinal regions / Int Radiat Oncol Biol Phys 73:1369~1375
Matuszak MM / 2010 / Clinical applications of volumetric modulated arc therapy / Int J Radiat Oncol Biol Phys 77:608~616
Sahgal A / 2008 / Stereotactic body radiosurgery for spinal metastases: a critical review / Int Radiat Oncol Biol Phys 71:652~665
Ingrid TK / 2010 / Volumetric modulated arc therapy versus conventional intensity modulated radiation therapy for stereotactic spine radiotherapy: A planning study and early clinical data / Radiother Oncol 94:224~228
Nelson JW / 2009 / Stereotactic body radiotherapy for lesions of the spine and paraspinal regions / Int Radiat Oncol Biol Phys 73:1369~1375
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