지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.10
- 수록면
- 472 - 479 (8page)
이용수
초록· 키워드
오류제보하기
BACKGROUND/OBJECTIVES: The goal of this study was to examine the effect of Sargassum coreanum extract (SCE) on blood glucose concentration and insulin resistance in C57BL-KsJ-db/db mice.
MATERIALS/METHODS: For 6 weeks, male C57BL/KsJ-db/db mice were administrated SCE (0.5%, w/w), and rosiglitazone (0.005%, w/w).
RESULTS: A supplement of the SCE for 6 weeks induced a significant reduction in blood glucose and glycosylated hemoglobin concentrations, and it improved hyperinsulinemia compared to the diabetic control db/db mice. The glucokinase activity in the hepatic glucose metabolism increased in the SCE-supplemented db/db mice, while phosphoenolpyruvate carboxykinase and glucose-6-phosphatase activities in the SCE-supplemented db/db mice were significantly lower than those in the diabetic control db/db mice. The homeostatic index of insulin resistance was lower in the SCE-supplemented db/db mice than in the diabetic control db/db mice.
CONCLUSIONS: These results suggest that a supplement of the SCE lowers the blood glucose concentration by altering the hepatic glucose metabolic enzyme activities and improves insulin resistance.
MATERIALS/METHODS: For 6 weeks, male C57BL/KsJ-db/db mice were administrated SCE (0.5%, w/w), and rosiglitazone (0.005%, w/w).
RESULTS: A supplement of the SCE for 6 weeks induced a significant reduction in blood glucose and glycosylated hemoglobin concentrations, and it improved hyperinsulinemia compared to the diabetic control db/db mice. The glucokinase activity in the hepatic glucose metabolism increased in the SCE-supplemented db/db mice, while phosphoenolpyruvate carboxykinase and glucose-6-phosphatase activities in the SCE-supplemented db/db mice were significantly lower than those in the diabetic control db/db mice. The homeostatic index of insulin resistance was lower in the SCE-supplemented db/db mice than in the diabetic control db/db mice.
CONCLUSIONS: These results suggest that a supplement of the SCE lowers the blood glucose concentration by altering the hepatic glucose metabolic enzyme activities and improves insulin resistance.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Sargassum coreanum extract alleviates hyperglycemia and improves insulin resistance in db/db diabetic mice
Nutrition Research and Practice
2015 .10
-
Tenebrio molitor (Mealworm) Extract Improves Insulin Sensitivity and Alleviates Hyperglycemia in C57BL/Ksj-db/db Mice
생명과학회지
2019 .05
-
Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice
Nutrition Research and Practice
2016 .10
-
Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice
Nutrition Research and Practice
2016 .10
-
Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice
Nutrition Research and Practice
2019 .02
-
Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice
Nutrition Research and Practice
2019 .02
-
데이터 표준설계와 통합데이터 포맷을 적용한 급경사지 공간정보 DB의 관계형 DB변환
대한지질학회 학술대회
2020 .10
-
Anti-diabetic effect of purple corn extract on C57BL/KsJ db/db mice
Nutrition Research and Practice
2015 .02
-
Anti-diabetic effect of purple corn extract on C57BL/KsJ db/db mice
Nutrition Research and Practice
2015 .02
-
발효 된장의 바이오제닉 아민 함량에 영향을 미치는 바실러스균의 분리 동정 및 프로바이오틱 특성
미생물학회지
2019 .06
-
국민건강보험공단의 표본연구DB를 위한 비주얼 쿼리 데이터베이스 시스템 개발 연구
응용통계연구
2017 .02
-
오메가-3 불포화지방산이 포함된 우지 섭취가 db/db 마우스의 지질대사 및 소포체 스트레스 반응에 미치는 영향
한국지역사회생활과학회 학술대회 자료집
2021 .11
-
Effect of Intestinal Microbiota Change on the Control of Obesity by the Use of Dapagliflozin and Butyrate Combination in db/db Mice
한국미생물학회 학술대회논문집
2019 .04
-
Anti-hyperglycemic effects and signaling mechanism of Perilla frutescens sprout extract
Nutrition Research and Practice
2018 .02
-
Anti-hyperglycemic effects and signaling mechanism of Perilla frutescens sprout extract
Nutrition Research and Practice
2018 .02
-
Coating rice with mulberry leaves rich in deoxynojirimycin ameliorates hyperglycemia and dyslipidemia in C57BL/KsJ db/db mice
Nutrition Research and Practice
2018 .12
-
Coating rice with mulberry leaves rich in deoxynojirimycin ameliorates hyperglycemia and dyslipidemia in C57BL/KsJ db/db mice
Nutrition Research and Practice
2018 .12
-
Highly water-soluble diacetyl chrysin ameliorates diabetes-associated renal fibrosis and retinal microvascular abnormality in db/db mice
Nutrition Research and Practice
2023 .06
-
Highly water-soluble diacetyl chrysin ameliorates diabetes-associated renal fibrosis and retinal microvascular abnormality in db/db mice
Nutrition Research and Practice
2023 .06
-
전통 발효 된장으로부터 분리된 바이오제닉 아민 생성 바실러스균에 대한 유산균의 항균 활성
미생물학회지
2018 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0