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논문 기본 정보

자료유형
학술저널
저자정보
Hyun In-Kyung (World Institute of Kimchi, Nam-Gu, Gwangju 61755, Republic of Korea) Hong Sung Wook (World Institute of Kimchi, Nam-Gu, Gwangju 61755, Republic of Korea) Ma Min-Ji (World Institute of Kimchi, Nam-Gu, Gwangju 61755, Republic of Korea) Chang Ji Yoon (World Institute of Kimchi, Nam-Gu, Gwangju 61755, Republic of Korea) Lee Seongsoo (Gwangju Center, Korea Basic Science Institute (KBSI), Gwangju 61751, Republic of Korea) Yun Ye-Rang (World Institute of Kimchi, Nam-Gu, Gwangju 61755, Republic of Korea)
저널정보
한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology Vol.34 No.1
발행연도
2024.1
수록면
123 - 131 (9page)
DOI
10.4014/jmb.2307.07005

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초록· 키워드

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Lactic acid bacteria (LAB) isolated from kimchi have various functions, including antioxidant, antiinflammation, and anti-obesity activities, and are therefore widely used in the food, pharmaceutical, and medical fields. To date, the health functionalities of LAB have been widely reported; however, those of kimchi fermented with LAB as a starter have rarely been reported. Therefore, research on the selection of LAB with anti-obesity activity and the health functionality of kimchi fermented with LAB is needed. In the present study, LAB with anti-obesity activity were initially selected by measuring the Oil-Red O intensity. Among the four LAB strains, anti-obesity activity was confirmed by measuring cell viability, lipid levels, and lipid accumulation. Then, starter kimchi (SK) was prepared by inoculating selected LABs, and its pH, total acidity, and salinity were compared with those of naturally fermented kimchi (NK). Lastly, anti-obesity activity was also investigated in 3T3- L1 cells. Selected LAB showed no cytotoxicity up to 107 CFU/ml, with Lactobacillus brevis JC7 and Leuconostoc mesenteroides KCKM0828 having higher inhibitory effects on TG, TC content and lipid accumulation. Most SKs showed fermentation properties similar to those of the NK. SKs showed no cytotoxicity at concentrations of up to 1,000 μg/ml. SKs showed strong inhibitory effects on TG content, lipid accumulation, and obesity-related gene and protein expressions. Taken together, the utilization of LAB as a starter could improve the health benefits of kimchi.

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